Lewis phenotypes, insulin resistance, and risk of ischaemic heart disease.

Lewis phenotypes, insulin resistance, and risk of ischaemic heart disease.

Lack of association between Lewis phenotypes and ischemic heart disease.

The Copenhagen Male Study found an increased risk of ischemic heart disease in men with the Lewis blood group phenotype Le(a-b-).1 This phenotype has also been associated with insulin-resistance syndrome, higher body mass index and hypertriglyceridemia in men but not in women.2 Alcohol consumption and a high level of leisure time physical activity have been found to be protective against ischem...

Fibrinogen, viscosity and ischaemic heart disease risk.

Relationship between obesity, insulin resistance, and coronary heart disease risk.

OBJECTIVES The study goals were to: 1) define the relationship between body mass index (BMI) and insulin resistance in 314 nondiabetic, normotensive, healthy volunteers; and 2) determine the relationship between each of these two variables and coronary heart disease (CHD) risk factors. BACKGROUND The importance of obesity as a risk factor for type 2 diabetes and hypertension is well-recognize...

Insulin resistance, diabetes, and risk markers for ischaemic heart disease in Asian men and non-Asian in Bradford.

OBJECTIVE To examine the hypothesis, in a community not studied before, that insulin resistance associated with centralised adiposity is the mechanism underlying the predisposition of Asian immigrant communities to both ischaemic heart disease and diabetes mellitus. DESIGN Cross sectional study within one socioeconomic stratum. SETTING Two factories in the textile sector in Bradford, West Y...